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Article

Genetic burden of MS risk variants distinguish patients from healthy individuals but are not associated with disease activity.

Multiple sclerosis and related disorders - 1 Apr 2017

Søndergaard Helle Bach, Petersen Eva Rosa, Magyari Melinda, Sellebjerg Finn, Oturai Annette Bang

Abstract excerpt

Weighted genetic risk score (wGRS) was analysed for association with disease activity in more than 500 MS patients before and during interferon-beta treatment. The wGRS was higher in MS patients than in healthy controls when analysing eight HLA - and 109 non-HLA MS risk gene variants. No significant associations were observed between number of relapses prior to or during treatment with interferon-beta, both with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28427696
DOI: 10.1016/j.msard.2017.01.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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