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Article

HMGN1 modulates estrogen-mediated transcriptional activation through interactions with specific DNA-binding transcription factors.

Molecular and cellular biology - 1 Dec 2007

Zhu Nan, Hansen Ulla

Abstract excerpt

HMGN1, an abundant nucleosomal binding protein, can affect both the chromatin higher order structure and the modification of nucleosomal histones, but it alters the expression of only a subset of genes. We investigated specific gene targeting by HMGN1 in the context of estrogen induction of gene expression. Knockdown and overexpression experiments indicated that HMGN1 limits the induction of several...

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Topics

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Share to Acetylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17938209
DOI: 10.1128/MCB.01724-07
PMCID: PMC2169410

Genes

HMGN1
TFF1
FOS
SRF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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