Article
Effects of HMGN variants on the cellular transcription profile.
Nucleic acids research - 1 May 2011
Rochman Mark, Taher Leila, Kurahashi Toshihiro, Cherukuri Srujana, Uversky Vladimir N, Landsman David, Ovcharenko Ivan, Bustin Michael
Abstract excerpt
High mobility group N (HMGN) is a family of intrinsically disordered nuclear proteins that bind to nucleosomes, alters the structure of chromatin and affects transcription. A major unresolved question is the extent of functional specificity, or redundancy, between the various members of the HMGN protein family. Here, we analyze the transcriptional profile of cells in which the expression of various HMGN proteins...
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