Back to search

Article

The HMGN Proteins Are Transcriptional Regulatory Factors in Humans

2025-11-28

Abstract excerpt

The high mobility group N (HMGN) proteins, which were discovered over 50 years ago, are a multigene family of abundant nucleosome-specific binding factors that are present in all vertebrates. Despite their intriguing nucleosome-binding activity, the potential functions of the HMGN proteins in chromatin have not yet been assessed unambiguously due to the presence of several related HMGN genes in vertebrates and th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ee24d398-c0bc-5bc0-bc82-9dee1df010ee
DOI
10.1101/2025.11.27.690916
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The HMGN Proteins Are Transcriptional Regulatory Factors in HumansDOI 10.1101/2025.11.27.690916
Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers.Semantic proximity
Effects of HMGN variants on the cellular transcription profile.Semantic proximity
HMGA1 in cancer: Cancer classification by locationSemantic proximity
HMG chromosomal proteins in development and disease.Semantic proximity
Distinct domains in high mobility group N variants modulate specific chromatin modifications.Semantic proximity
Role of HMGB1 and its associated signaling pathways in human malignanciesSemantic proximity
HMGN proteins act in opposition to ATP-dependent chromatin remodeling factors to restrict nucleosome mobility.Semantic proximity
HMGA proteins: isolation, biochemical modifications, and nucleosome interactions.Semantic proximity
Multiple functions of HMGB1 in cancerSemantic proximity
HMGB1: The jack‐of‐all‐trades protein is a master DNA repair mechanicSemantic proximity
High Mobility Group Box 1 (HMGB1): Molecular Signaling and Potential Therapeutic StrategiesSemantic proximity
Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine functionSemantic proximity
Select a neighboring publication to make it the new centre.