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Article

Chromosomal protein HMGN1 modulates the expression of N-cadherin.

The FEBS journal - 1 Nov 2005

Rubinstein Yaffa R, Furusawa Takashi, Lim Jae-Hwan, Postnikov Yuri V, West Katherine L, Birger Yehudit, Lee Sunmin, Nguyen Phuongmai, Trepel Jane B, Bustin Michael

Abstract excerpt

HMGN1 is a nuclear protein that binds to nucleosomes and alters the accessibility of regulatory factors to their chromatin targets. To elucidate its biological function and identify specific HMGN1 target genes, we generated Hmgn1-/- mice. DNA microarray analysis of Hmgn1+/+ and Hmgn1-/- embryonic fibroblasts identified N-cadherin as a potential HMGN1 gene target. RT-PCR and western blot analysis confirmed a...

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Source

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Identifiers

PMID: 16279949
DOI: 10.1111/j.1742-4658.2005.04980.x
PMCID: PMC3730465

Genes

HMGN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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