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Article

Distinct domains in high mobility group N variants modulate specific chromatin modifications.

The Journal of biological chemistry - 14 Apr 2006

Ueda Tetsuya, Postnikov Yuri V, Bustin Michael

Abstract excerpt

We have demonstrated that levels of specific modification in histone H3 are modulated by members of the nucleosome-binding high mobility group N (HMGN) protein family in a variant-specific manner. HMGN1 (but not HMGN2) inhibits the phosphorylation of both H3S10 and H3S28, whereas HMGN2 enhances H3K14 acetylation more robustly than HMGN1. Two HMGN domains are necessary for modulating chromatin modifications, a...

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Share to Acetylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Erythrocytes

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Source

Identifiers

PMID: 16484217
DOI: 10.1074/jbc.M600821200

Genes

HMGN1
HMGN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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