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Article

Chromosomal protein HMGN1 enhances the acetylation of lysine 14 in histone H3.

The EMBO journal - 7 Sept 2005

Lim Jae-Hwan, West Katherine L, Rubinstein Yaffa, Bergel Michael, Postnikov Yuri V, Bustin Michael

Abstract excerpt

The acetylation levels of lysine residues in nucleosomes, which are determined by the opposing activities of histone acetyltransferases (HATs) and deacetylases, play an important role in regulating chromatin-related processes, including transcription. We report that HMGN1, a nucleosomal binding protein that reduces the compaction of the chromatin fiber, increases the levels of acetylation of K14 in H3. The levels...

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Share to Acetylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16096646
DOI: 10.1038/sj.emboj.7600768
PMCID: PMC1201349

Genes

HMGN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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