Article

Identification of genomic features that uniquely impact estrogen receptor alpha binding and its effects on gene expression in endometrial cancer

2025-12-15

Abstract excerpt

Estrogen receptor alpha (ER) is an established oncogenic transcription factor in breast and endometrial cancer; however, more is known about the mechanisms controlling ER behavior in breast cancer, and therapies targeting ER have been much more successful in breast cancer. To address this disparity, we characterize the genomic features that control ER in endometrial cancer and determine to what extent these factor...

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Literature Corpus work: 2270cc8b-7f51-5c65-8868-f54d85154a22
DOI: 10.64898/2025.12.11.693723

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