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Article

Gene variations in GSTM3 are a risk factor for Alzheimer's disease.

Neurobiology of aging - 1 May 2009

Hong G-S, Heun R, Jessen F, Popp J, Hentschel F, Kelemen P, Schulz A, Maier W, Kölsch H

Abstract excerpt

Oxidative stress is a relevant pathomechanism in Alzheimer's disease (AD) and gene variations in the glutathione S-transferase M3 gene (GSTM3), involved in the detoxification of oxygen radicals, might influence the risk of AD. We investigated the effect of three polymorphisms in GSTM3: rs1332018 (C/A); rs1799735 (del/AGG); rs7483 (G/A), on the risk of AD in 363 AD patients and 358 healthy controls. Single marker...

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Source

Identifiers

PMID: 17904251
DOI: 10.1016/j.neurobiolaging.2007.08.012

Genes

GSTM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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