Article
Association of glutathione S-transferases M1, P1 and T1 variations and risk of late-onset Alzheimer's disease.
Neurological research - 1 Jan 2018
Jafarian Zahra, Saliminejad Kioomars, Kamali Koorosh, Ohadi Mina, Kowsari Ali, Nasehi Leila, Khorram Khorshid Hamid Reza
Abstract excerpt
OBJECTIVE: Late-onset Alzheimer's disease (AD) is a genetically heterogeneous neurodegenerative disorder. Associations of the glutathione S-transferases (GSTs) polymorphisms with the risk factors for AD have not been definitely confirmed. We investigated the association of GSTM1 and GSTT1 null deletion and GSTP1 313 A/G polymorphisms and the risk of AD in an Iranian population. METHODS: The case group consisted...
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