A GSTM3 polymorphism associated with an etiopathogenetic mechanism in Alzheimer disease.

doi:10.1016/j.neurobiolaging.2008.03.007

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A GSTM3 polymorphism associated with an etiopathogenetic mechanism in Alzheimer disease.

Neurobiology of aging - 1 Jan 2010

Maes Olivier C, Schipper Hyman M, Chong George, Chertkow Howard M, Wang Eugenia

Abstract excerpt

Brain-specific glutathione S-transferase Mu 3 (GSTM3) colocalizes with amyloid-beta plaques in Alzheimer's disease (AD). A functional polymorphism rs7483 in GSTM3 may contribute to the decrease in GSTM3 expression in AD. The association of the rs7483 SNP with late-onset AD and mild cognitive impa...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antioxidants

Share to Brain

Share to DNA Repair

Share to Down-Regulation

Share to Genetic Testing

Share to Glutathione Transferase

Share to Leukocytes, Mononuclear

Source

Open in PubMed

Identifiers

PMID: 18423940
DOI: 10.1016/j.neurobiolaging.2008.03.007

Genes

GSTM3
MCM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18423940-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A GSTM3 polymorphism associated with an etiopathogenetic mechanism in Alzheimer disease.PMID 18423940Read ↗

Gene variations in GSTM3 are a risk factor for Alzheimer's disease.Semantic proximity Read ↗

Genetic variants in GSTM3 gene within GSTM4-GSTM2-GSTM1-GSTM5-GSTM3 cluster influence breast cancer susceptibility depending on GSTM1.Semantic proximity Read ↗

PLD3 epigenetic changes in the hippocampus of Alzheimer's disease.Semantic proximity Read ↗

Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: an association study with mechanistic implications.Semantic proximity Read ↗

DNMT3B promoter polymorphisms and risk of late onset Alzheimer's disease.Semantic proximity Read ↗

Expression-based discovery of variation in the human glutathione S-transferase M3 promoter and functional analysis in a glioma cell line using allele-specific chromatin immunoprecipitation.Semantic proximity Read ↗

Glutathione S-transferases variants as risk factors in Alzheimer's disease.Semantic proximity Read ↗

Glutathione S-transferase P1 *C allelic variant increases susceptibility for late-onset Alzheimer disease: association study and relationship with apolipoprotein E epsilon4 allele.Semantic proximity Read ↗

Glutathione S-transferase variants increase susceptibility for late-onset Alzheimer's disease: association study and relationship with apolipoprotein E epsilon4 allele.Semantic proximity Read ↗

Post-GWAS multiomic functional investigation of the TNIP1 locus in Alzheimer's disease highlights a potential role for GPX3.Semantic proximity Read ↗

An international case-control study of glutathione transferase and functionally related polymorphisms and risk of primary adult brain tumors.Semantic proximity Read ↗

Examination of MGMT as a risk gene for dementia in the Amish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.