Article
Polymorphisms in glutathione S-transferase omega-1 gene and increased risk of sporadic Alzheimer disease.
Rejuvenation research - 1 Dec 2010
Capurso Cristiano, Panza Francesco, Seripa Davide, Frisardi Vincenza, Imbimbo Bruno P, Verdile Gerardo, Vendemiale Gianluigi, Pilotto Alberto, Solfrizzi Vincenzo
Abstract excerpt
Previous studies examining the association between the glutathione S-transferase omega-1 (GSTO1) single-nucleotide polymorphisms (SNPs) and Alzheimer disease (AD) have yielded conflicting results. Furthermore, an effect of GSTO1 rs4925 on the age-at-onset (AAO) of AD was found in different studies on sporadic and familial AD cases, but with contrasting findings. A total sample of 103 AD patients, and 157 age- and...
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