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Genetic variants in GSTM3 gene within GSTM4-GSTM2-GSTM1-GSTM5-GSTM3 cluster influence breast cancer susceptibility depending on GSTM1.

Breast cancer research and treatment - 1 Jun 2010

Yu Ke-Da, Fan Lei, Di Gen-Hong, Yuan Wen-Tao, Zheng Ying, Huang Wei, Chen Ao-Xiang, Yang Chen, Wu Jiong, Shen Zhen-Zhou, Shao Zhi-Ming

Abstract excerpt

Mu class of Glutathione-S-transferase (GSTM) genes arrange in a tandem on chromosome 1p13.3. The relationship between genetic variants in the GSTM1-5 gene cluster and breast cancer is still ambiguous. In the present study, 17 tagging single-nucleotide polymorphisms (SNPs) covering the GSTMs cluster were originally selected and 11 validated SNPs were used for genotyping 921 cases and 711 controls. The association...

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Source

Identifiers

PMID: 19856098
DOI: 10.1007/s10549-009-0585-9

Genes

GSTM1
GSTM3
GSTM2
GSTM4
GSTM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variants in GSTM3 gene within GSTM4-GSTM2-GSTM1-GSTM5-GSTM3 cluster influence breast cancer susceptibility depending on GSTM1.PMID 19856098Read ↗

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