Article
The glutathione S-transferase polymorphisms in a control population and in Alzheimer's disease patients.
Clinical chemistry and laboratory medicine - 1 Mar 2004
Zuntar Irena, Kalanj-Bognar Svjetlana, Topić Elizabeta, Petlevski Roberta, Stefanović Mario, Demarin Vida
Abstract excerpt
In this study, we investigated the role of glutathione S-transferase P1 (GSTP1) polymorphisms in the pathogenesis of Alzheimer's disease (AD). We genotyped the GSTP1 polymorphisms in exon 5 (A313G) and exon 6 (C341T) by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in 56 Croatian patients with AD and 231 controls. Distributions and frequencies of GSTP1 genetic variants were not...
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