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Article

Elg1 forms an alternative RFC complex important for DNA replication and genome integrity.

The EMBO journal - 15 Aug 2003

Bellaoui Mohammed, Chang Michael, Ou Jiongwen, Xu Hong, Boone Charles, Brown Grant W

Abstract excerpt

Genome-wide synthetic genetic interaction screens with mutants in the mus81 and mms4 replication fork-processing genes identified a novel replication factor C (RFC) homolog, Elg1, which forms an alternative RFC complex with Rfc2-5. This complex is distinct from the DNA replication RFC, the DNA damage checkpoint RFC and the sister chromatid cohesion RFC. As expected from its genetic interactions, elg1 mutants are...

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Identifiers

PMID: 12912927
DOI: 10.1093/emboj/cdg406
PMCID: PMC175796

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