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Article

Interplay between Fanconi anemia and homologous recombination pathways in genome integrity.

The EMBO journal - 2 May 2016

Michl Johanna, Zimmer Jutta, Tarsounas Madalena

Abstract excerpt

The Fanconi anemia (FA) pathway plays a central role in the repair of DNA interstrand crosslinks (ICLs) and regulates cellular responses to replication stress. Homologous recombination (HR), the error-free pathway for double-strand break (DSB) repair, is required during physiological cell cycle progression for the repair of replication-associated DNA damage and protection of stalled replication forks. Substantial...

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Share to DNA Repair
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27037238
DOI: 10.15252/embj.201693860
PMCID: PMC4865030

Genes

BRCA1
BRCA2
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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