Article
ISWI regulates higher-order chromatin structure and histone H1 assembly in vivo.
PLoS biology - 1 Sept 2007
Corona Davide F V, Siriaco Giorgia, Armstrong Jennifer A, Snarskaya Natalia, McClymont Stephanie A, Scott Matthew P, Tamkun John W
Abstract excerpt
Imitation SWI (ISWI) and other ATP-dependent chromatin-remodeling factors play key roles in transcription and other processes by altering the structure and positioning of nucleosomes. Recent studies have also implicated ISWI in the regulation of higher-order chromatin structure, but its role in this process remains poorly understood. To clarify the role of ISWI in vivo, we examined defects in chromosome structure...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
