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Article

Widespread collaboration of Isw2 and Sin3-Rpd3 chromatin remodeling complexes in transcriptional repression.

Molecular and cellular biology - 1 Oct 2001

Fazzio T G, Kooperberg C, Goldmark J P, Neal C, Basom R, Delrow J, Tsukiyama T

Abstract excerpt

The yeast Isw2 chromatin remodeling complex functions in parallel with the Sin3-Rpd3 histone deacetylase complex to repress early meiotic genes upon recruitment by Ume6p. For many of these genes, the effect of an isw2 mutation is partially masked by a functional Sin3-Rpd3 complex. To identify the full range of genes repressed or activated by these factors and uncover hidden targets of Isw2-dependent regulation,...

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Identifiers

PMID: 11533234
DOI: 10.1128/MCB.21.19.6450-6460.2001
PMCID: PMC99792

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Widespread collaboration of Isw2 and Sin3-Rpd3 chromatin remodeling complexes in transcriptional repression.PMID 11533234Read ↗

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