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Article

Dynamic Control of X Chromosome Conformation and Repression by a Histone H4K20 Demethylase.

Cell - 21 Sept 2017

Brejc Katjuša, Bian Qian, Uzawa Satoru, Wheeler Bayly S, Anderson Erika C, King David S, Kranzusch Philip J, Preston Christine G, Meyer Barbara J

Abstract excerpt

Chromatin modification and higher-order chromosome structure play key roles in gene regulation, but their functional interplay in controlling gene expression is elusive. We have discovered the machinery and mechanism underlying the dynamic enrichment of histone modification H4K20me1 on hermaphrodite X chromosomes during C. elegans dosage compensation and demonstrated H4K20me1's pivotal role in regulating...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dosage Compensation, Genetic

Share to Embryo, Nonmammalian

Share to Jumonji Domain-Containing Histone Demethylases

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Identifiers

PMID: 28867287
DOI: 10.1016/j.cell.2017.07.041
PMCID: PMC5678999

Genes

DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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