Article
The nucleosome remodeling factor ISWI functionally interacts with an evolutionarily conserved network of cellular factors.
Genetics - 1 May 2010
Arancio Walter, Onorati Maria C, Burgio Giosalba, Collesano Marianna, Ingrassia Antonia M R, Genovese Swonild I, Fanto Manolis, Corona Davide F V
Abstract excerpt
ISWI is an evolutionarily conserved ATP-dependent chromatin remodeling factor playing central roles in DNA replication, RNA transcription, and chromosome organization. The variety of biological functions dependent on ISWI suggests that its activity could be highly regulated. Our group has previously isolated and characterized new cellular activities that positively regulate ISWI in Drosophila melanogaster. To...
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