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Article

The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p.

Cell - 27 Oct 2000

Goldmark J P, Fazzio T G, Estep P W, Church G M, Tsukiyama T

Abstract excerpt

The ISWI class of chromatin remodeling factors exhibits potent chromatin remodeling activities in vitro. However, the in vivo functions of this class of factors are unknown at a molecular level. We have found that S. cerevisiae Isw2 complex represses transcription of early meiotic genes during mitotic growth in a parallel pathway to Rpd3-Sin3 histone deacetylase complex. This repressor function of lsw2 complex is...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11081629
DOI: 10.1016/s0092-8674(00)00134-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p.PMID 11081629Read ↗

Widespread collaboration of Isw2 and Sin3-Rpd3 chromatin remodeling complexes in transcriptional repression.Semantic proximity Read ↗

Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae.Semantic proximity Read ↗

Yeast Isw1p forms two separable complexes in vivo.Semantic proximity Read ↗

Isw1 functions in parallel with the NuA4 and Swr1 complexes in stress-induced gene repression.Semantic proximity Read ↗

Two distinct mechanisms of chromatin interaction by the Isw2 chromatin remodeling complex in vivo.Semantic proximity Read ↗

Functional antagonism between Sas3 and Gcn5 acetyltransferases and ISWI chromatin remodelers.Semantic proximity Read ↗

Global role for chromatin remodeling enzymes in mitotic gene expression.Semantic proximity Read ↗

Genomic footprinting of the yeast zinc finger protein Rme1p and its roles in repression of the meiotic activator IME1.Semantic proximity Read ↗

Positive control of yeast meiotic genes by the negative regulator UME6.Semantic proximity Read ↗

Identification of the Sin3-binding site in Ume6 defines a two-step process for conversion of Ume6 from a transcriptional repressor to an activator in yeast.Semantic proximity Read ↗

Swc2 is a widely conserved H2AZ-binding module essential for ATP-dependent histone exchange.Semantic proximity Read ↗

The ISWI chromatin-remodeling protein is required for gene expression and the maintenance of higher order chromatin structure in vivo.Semantic proximity Read ↗

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