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Article

Maternal depletion of Piwi, a component of the RNAi system, impacts heterochromatin formation in Drosophila.

PLoS genetics - 1 Jan 2013

Gu Tingting, Elgin Sarah C R

Abstract excerpt

A persistent question in epigenetics is how heterochromatin is targeted for assembly at specific domains, and how that chromatin state is faithfully transmitted. Stable heterochromatin is necessary to silence transposable elements (TEs) and maintain genome integrity. Both the RNAi system and heterochromatin components HP1 (Swi6) and H3K9me2/3 are required for initial establishment of heterochromatin structures in...

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Identifiers

PMID: 24068954
DOI: 10.1371/journal.pgen.1003780
PMCID: PMC3777992

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Maternal depletion of Piwi, a component of the RNAi system, impacts heterochromatin formation in Drosophila.PMID 24068954Read ↗

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