Article

Mutations in the Insulator Protein Suppressor of Hairy Wing Induce Genome Instability

2019-02-15

Abstract excerpt

Chromatin insulator proteins mediate the formation of contacts between distant insulator sites along chromatin fibers. Long-range contacts facilitate communication between regulatory sequences and gene promoters throughout the genome, allowing accurate gene transcription regulation during embryo development and cell differentiation. Lack of insulator function has detrimental effects often resulting in lethality. T...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b6bd5398-accb-5b22-9b28-d626beaa7df6
DOI: 10.1101/551002

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mutations in the Insulator Protein Suppressor of Hairy Wing Induce Genome InstabilityDOI 10.1101/551002Read

Mutations in the insulator protein Suppressor of Hairy wing induce genome instability.Semantic proximity Read

The role of the Suppressor of Hairy-wing insulator protein in Drosophila oogenesis.Semantic proximity Read

A Drosophila insulator interacting protein suppresses enhancer-blocking function and modulates replication timing.Semantic proximity Read

Genome organization regulates nuclear pore complex formation and promotes differentiation during Drosophila oogenesisSemantic proximity Read

Pleiotropic Functions of the Chromodomain-Containing Protein Hat-trick During Oogenesis in Drosophila melanogaster.Semantic proximity Read

Drosophila <i>small ovary</i> gene ensures germline stem cell maintenance and differentiation by silencing transposons and organising heterochromatinSemantic proximity Read

Genome-wide studies of the multi-zinc finger Drosophila Suppressor of Hairy-wing protein in the ovary.Semantic proximity Read

Hrb27C, Sqd and Otu cooperatively regulate gurken RNA localization and mediate nurse cell chromosome dispersion in Drosophila oogenesis.Semantic proximity Read

Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesisSemantic proximity Read

Stonewall prevents expression of testis-enriched genes and binds to insulator elements in <i>D. melanogaster</i>Semantic proximity Read

zucchini and squash encode two putative nucleases required for rasiRNA production in the Drosophila germline.Semantic proximity Read

Investigation of the properties of non-gypsy suppressor of hairy-wing-binding sites.Semantic proximity Read