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Article

A1298C polymorphism of the MTHFR gene and neural tube defects in the state of Yucatan, Mexico.

Birth defects research. Part A, Clinical and molecular teratology - 1 Aug 2007

Gonzalez-Herrera Lizbeth, Castillo-Zapata Ileana, Garcia-Escalante Guadalupe, Pinto-Escalante Doris

Abstract excerpt

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) of the folate metabolism pathway is a candidate gene for neural tube defects (NTDs). Frequency of the second common polymorphism, A1298C, in the MTHFR gene is not well known in Mexico. Conflicting results exist regarding the association of A1298C-MTHFR with NTDs. One explanation for this controversy might be that alleles are differently distributed among...

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Source

Identifiers

PMID: 17621650
DOI: 10.1002/bdra.20381

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A1298C polymorphism of the MTHFR gene and neural tube defects in the state of Yucatan, Mexico.PMID 17621650Read ↗

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