Article
Lack of association between the methylenetetrahydropholate reductase gene A1298C polymorphism and neural tube defects in a Turkish study group.
Genetics and molecular research : GMR - 3 Jun 2016
Yildiz S H, Ozdemir Erdogan M, Solak M, Eser O, Arıkan Terzi E S, Eser B, Kocabaş V, Aslan A
Abstract excerpt
The etiology underlying neural tube defects (NTDs) is not fully understood and is believed to involve a complex milieu of genetic and environmental factors. The A1298C polymorphism in the methylenetetrahydropholate reductase gene (MTHFR) has been associated with mild risk for NTDs. In this study, the genotype distribution of the MTHFR gene A1298C polymorphism and the levels of serum homocysteine, vitamin B12, and...
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