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Article

Association between MTHFR A1298C polymorphism and neural tube defect susceptibility: a metaanalysis.

American journal of obstetrics and gynecology - 1 Mar 2012

Wang Xi W, Luo Ya L, Wang Wei, Zhang Yu, Chen Qing, Cheng Yu L

Abstract excerpt

OBJECTIVE: To determine whether 5,10-methylenetetrahydrofolate reductase A1298C polymorphism is associated with neural tube defect susceptibility. STUDY DESIGN: Computerized literature searches of the PubMed, Embase, and Medline database were conducted to identify all eligible articles. Study subjects were classified as neural tube defect patients, mothers with neural tube defect offspring and fathers with neural...

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Source

Identifiers

PMID: 22265089
DOI: 10.1016/j.ajog.2011.12.021

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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