Article
Methylenetetrahydrofolate reductase gene polymorphisms and the risk of anencephaly in Mexico.
Molecular human reproduction - 1 Jun 2007
Muñoz Julia Blanco, Lacasaña Marina, Cavazos Ricardo García, Borja-Aburto Victor Hugo, Galavíz-Hernández Carlos, Garduño Clemente Aguilar
Abstract excerpt
The precise etiology of neural tube defects (NTDs) is not known. There is some evidence that mutations in MTHFR gene provide susceptibility to NTDs in some populations; however, other studies have not found this association. One of the problems with previous studies is that they treat NTDs as a homogeneous group, when specific defects could have different etiologies. We conducted a case-control study specifically...
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