Article
P53 gene mutations in surgical margins and primary tumor tissues of patients with squamous cell carcinoma of the head and neck.
Tumori - 1 Jan 2000
Tunca Berrin, Erisen Levent, Coskun Hakan, Cecener Gulsah, Ozuysal Sema, Egeli Unal
Abstract excerpt
AIMS AND BACKGROUND: The frequency of p53 mutations in primary tumors, the effect of the mutations on some clinical and pathological features of head and neck squamous cell carcinoma, and the impact of p53 mutations in the surgical margins on local recurrence were determined, MATERIAL AND METHODS: We investigated the presence of p53 mutations in primary tumor samples and in the surgical margins of 34 patients...
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