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Article

Molecular diagnosis of surgical margins and local recurrence in head and neck cancer patients: a prospective study.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2004

van Houten Viola M M, Leemans C René, Kummer J Alain, Dijkstra Janny, Kuik Dirk J, van den Brekel Michiel W M, Snow Gordon B, Brakenhoff Ruud H

Abstract excerpt

PURPOSE: Approximately 10-30% of surgically treated head and neck cancer patients develop local recurrences while the resection margins are histologically tumor free. These recurrences may arise from cancer cells left behind but not detected by the pathologist, or they may develop from precursor lesions adjacent to the tumor that were not completely resected. We have investigated whether TP53-mutated DNA in the...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasm Recurrence, Local

Share to Neoplasm, Residual

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Source

Identifiers

PMID: 15173067
DOI: 10.1158/1078-0432.CCR-03-0631

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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