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Article

Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck.

The New England journal of medicine - 16 Feb 1995

Brennan J A, Mao L, Hruban R H, Boyle J O, Eby Y J, Koch W M, Goodman S N, Sidransky D

Abstract excerpt

BACKGROUND: Surgical oncologists rely heavily on the histopathological assessment of surgical margins to ensure total excision of the tumor in patients with head and neck cancer. However, current techniques may not detect small numbers of cancer cells at the margins of resection or in cervical lymph nodes. METHODS: We used molecular techniques to determine whether clonal populations of infiltrating tumor cells...

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Source

Identifiers

PMID: 7619114
DOI: 10.1056/NEJM199502163320704

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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