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Article

Patterns of p53 gene mutations in head and neck cancer: full-length gene sequencing and results of primary radiotherapy.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 1999

Saunders M E, MacKenzie R, Shipman R, Fransen E, Gilbert R, Jordan R C

Abstract excerpt

p53 gene alterations are common in head and neck cancers, but their prognostic value has not been clearly established. Despite evidence in other cancers that sequencing of the entire p53 coding region provides prognostic information, full-length p53 gene sequencing has rarely been performed in head and neck cancers. In this study, p53 was assessed in a series of 42 pretreatment biopsies from patients with...

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PMID: 10499619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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