Article
Androgen-mediated immune function is altered by the apolipoprotein E gene.
Endocrinology - 1 Jul 2007
Brown Candice M, Xu Qing, Okhubo Nobutaka, Vitek Michael P, Colton Carol A
Abstract excerpt
Androgens, like estrogens, have been linked to neuroprotective effects in the brain and to the improvement of cognitive function. Part of this effect may be due to the action of androgens on the innate immune response. We have examined the action of dihydrotestosterone (DHT) and testosterone on immune activation in primary cultures of microglia, the central nervous system macrophage. Our data indicate that DHT...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.