Article
Sequence variation within the major histocompatibility complex subregion centromeric of HLA class II in type 1 diabetes.
Tissue antigens - 1 Apr 2007
van der Slik A R, van den Eng I, Eerligh P, Doxiadis I I N, Koeleman B P C, Roep B O, Giphart M J
Abstract excerpt
The extended major histocompatibility complex (xMHC) has been studied intensively with regard to type 1 diabetes (T1D) predisposition. So far, little attention has been given to the subregion centromeric of MHC class II. We selected five single nucleotide polymorphisms in genes with potential immune-related functions in the genomic regions of death-domain-associated protein 6 (DAXX, apoptosis associated),...
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