Article
Dominant sequences of human major histocompatibility complex conserved extended haplotypes from HLA-DQA2 to DAXX.
PLoS genetics - 1 Oct 2014
Larsen Charles E, Alford Dennis R, Trautwein Michael R, Jalloh Yanoh K, Tarnacki Jennifer L, Kunnenkeri Sushruta K, Fici Dolores A, Yunis Edmond J, Awdeh Zuheir L, Alper Chester A
Abstract excerpt
We resequenced and phased 27 kb of DNA within 580 kb of the MHC class II region in 158 population chromosomes, most of which were conserved extended haplotypes (CEHs) of European descent or contained their centromeric fragments. We determined the single nucleotide polymorphism and deletion-insertion polymorphism alleles of the dominant sequences from HLA-DQA2 to DAXX for these CEHs. Nine of 13 CEHs remained...
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