Article
No evidence of type 1 diabetes susceptibility genes in the region centromeric of the HLA complex.
Human immunology - 1 Oct 2003
Johansson Stefan, Lie Benedicte A, Cambon-Thomsen Anne, Pociot Flemming, Nerup Jørn, Kockum Ingrid, Thorsby Erik, Undlien Dag E
Abstract excerpt
There is strong evidence that DQB1, DQA1, and DRB1 alleles are not the only contributors to the human leukocyte antigen (HLA) linked type 1 diabetes (T1D) predisposition. Although the HLA complex is much studied for disease association, little is known about the neighboring centromeric region. We have previously found suggestive association on DQ2-DR3 haplotypes for marker D6S291, located 3.6-Mb centromeric of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.