Article
HLA-G 14-bp polymorphism affects the age of onset in Type I Diabetes Mellitus.
International journal of immunogenetics - 1 Jun 2016
Gerasimou P, Skordis N, Picolos M, Spyridonidis A, Costeas P
Abstract excerpt
Type I diabetes mellitus (T1DM) is an organ-specific autoimmune disorder affecting the insulin-producing pancreatic cells. T1DM genetic association studies have so far revealed the involvement of more than 40 loci, with particularly strong associations for the human leucocyte antigens (HLA). Further to the well-established HLA class II associations, the immunomodulatory elements in the telomeric major...
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