Article
Analysis of HLA genotypes and susceptibility to insulin-dependent diabetes mellitus: association maps telomeric to HLA-DP.
Scandinavian journal of immunology - 1 Aug 1992
Baisch J M, Capra J D
Abstract excerpt
There is convincing evidence that certain combinations of alleles within the human leucocyte antigen (HLA) complex, particularly within HLA-DQ, are associated with either resistance or susceptibility to insulin-dependent diabetes mellitus (IDDM). A previous study conducted on a large, well-defined group of patients demonstrated that DQB1*0302 (DQw8) conferred 'dominant susceptibility' to IDDM while DQB1*0602...
Topics
- Adolescent
- Adult
- Alleles
- Chromosome Mapping
- Diabetes Mellitus, Type 1
- Female
- Genotype
- HLA-DP Antigens
- HLA-DQ Antigens
- HLA-DR Antigens
- Humans
- Male
