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Article

TAP1 alleles in insulin-dependent diabetes mellitus: a newly defined centromeric boundary of disease susceptibility.

Proceedings of the National Academy of Sciences of the United States of America - 1 Dec 1993

Jackson D G, Capra J D

Abstract excerpt

It has been previously demonstrated that individuals with certain DR alleles have an increased relative risk of developing insulin-dependent diabetes mellitus (IDDM). The disease association is even stronger with certain DQ alleles but there is little association with DP providing a boundary of disease association to the 430 kb between DQ and DP. The recently described TAP (transporter associated with antigen...

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Identifiers

PMID: 8248212
DOI: 10.1073/pnas.90.23.11079
PMCID: PMC47925

Genes

TAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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TAP1 alleles in insulin-dependent diabetes mellitus: a newly defined centromeric boundary of disease susceptibility.PMID 8248212Read ↗

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Genetic heterogeneity between type 1a and type 1b insulin-dependent diabetes mellitus: HLA class II and TAP gene analysis.Semantic proximity Read ↗

Extreme genetic risk for type 1A diabetes in the post-genome era.Semantic proximity Read ↗

Polymorphisms of TAP1 and TAP2 genes in German patients with type 1 diabetes mellitus.Semantic proximity Read ↗

Analysis of TAP2 polymorphisms in Finnish individuals with type I diabetes.Semantic proximity Read ↗

Susceptibility to insulin-dependent diabetes mellitus and short cytoplasmic ATP-binding domain TAP2*01 alleles.Semantic proximity Read ↗

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Insulin-dependent diabetes mellitus and the major histocompatibility complex peptide transporters TAP1 and TAP2: no association in a population with a high disease incidence.Semantic proximity Read ↗

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