Article
TAP1 alleles in insulin-dependent diabetes mellitus: a newly defined centromeric boundary of disease susceptibility.
Proceedings of the National Academy of Sciences of the United States of America - 1 Dec 1993
Jackson D G, Capra J D
Abstract excerpt
It has been previously demonstrated that individuals with certain DR alleles have an increased relative risk of developing insulin-dependent diabetes mellitus (IDDM). The disease association is even stronger with certain DQ alleles but there is little association with DP providing a boundary of d...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP-Binding Cassette Transporters
- Alleles
- Base Sequence
- Carrier Proteins
- Centromere
- Chromosome Mapping
- DNA Primers
- Diabetes Mellitus, Type 1
- Gene Frequency
- Genes, MHC Class II
- Genetic Linkage
- Histocompatibility Antigens Class II
- Humans
- Molecular Sequence Data
- Sequence Alignment
- Sequence Homology, Nucleic Acid