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Article

The MHC type 1 diabetes susceptibility gene is centromeric to HLA-DQB1.

Journal of autoimmunity - 1 Jun 2008

Husain Zaheed, Kelly M Ann, Eisenbarth George S, Pugliese Alberto, Awdeh Zuheir L, Larsen Charles E, Alper Chester A

Abstract excerpt

HLA-DQB1 is widely considered to be the major histocompatibility complex (MHC) susceptibility gene for type 1 diabetes (T1D). However, since inheritance of the gene in T1D is recessive, the presence of the protective HLA-DQB1 0602 allele with normal nucleotide sequence in some patients raises the question of whether HLA-DQB1 is not the susceptibility locus itself but merely a good marker. HLA-DQB1 0602 is part of...

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Identifiers

PMID: 18065200
DOI: 10.1016/j.jaut.2007.10.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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