Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in the FCN2 gene determine serum variation and function of Ficolin-2

6 May 2005

Abstract excerpt

The ficolin 1, 2 and 3 (derived from the FCN1, 2 and 3 genes, respectively) are homologous soluble pattern recognition molecules of importance for innate immunity, comprising collagen-like and fibrinogen-like domains, binding to sugar groups on different types of microorganisms. Serum concentration of Ficolin-2 varies considerably in healthy individuals. Thus, we speculated whether this could be due to variations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Coagulation and Thrombosis Mechanisms
Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
Share to Complement system in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15879437
DOI: 10.1093/hmg/ddi173

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in the FCN2 gene determine serum variation and function of Ficolin-2PMID 15879437Read ↗

The impact of FCN2 polymorphisms and haplotypes on the Ficolin-2 serum levels.Semantic proximity Read ↗

Functional SNPs in the human ficolin (FCN) genes reveal distinct geographical patterns.Semantic proximity Read ↗

Reliable and rapid characterization of functional FCN2 gene variants reveals diverse geographical patterns.Semantic proximity Read ↗

MBL2, FCN1, FCN2 and FCN3-The genes behind the initiation of the lectin pathway of complement.Semantic proximity Read ↗

Non-synonymous polymorphisms in the FCN1 gene determine ligand-binding ability and serum levels of M-ficolin.Semantic proximity Read ↗

Variation in FCN1 affects biosynthesis of ficolin-1 and is associated with outcome of systemic inflammation.Semantic proximity Read ↗

Coding and non-coding polymorphisms in the lectin pathway activator L-ficolin gene in 188 Dutch blood bank donors.Semantic proximity Read ↗

Ficolin 2 (FCN2) functional polymorphisms and the risk of rheumatic fever and rheumatic heart disease.Semantic proximity Read ↗

Polymorphisms in FCN genes and their influence on systemic lupus erythematosus susceptibility: a report from Western India.Semantic proximity Read ↗

Polymorphisms of the FCN2 Gene 3'UTR Region and Their Clinical Associations in Preterm Newborns.Semantic proximity Read ↗

Novel FCN2 Variants and Haplotypes are Associated with Rheumatic Heart Disease.Semantic proximity Read ↗

Genetic evidence of functional ficolin-2 haplotype as susceptibility factor in cutaneous leishmaniasis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.