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Article

Non-synonymous polymorphisms in the FCN1 gene determine ligand-binding ability and serum levels of M-ficolin.

PloS one - 1 Jan 2012

Ammitzbøll Christian Gytz, Kjær Troels Rønn, Steffensen Rudi, Stengaard-Pedersen Kristian, Nielsen Hans Jørgen, Thiel Steffen, Bøgsted Martin, Jensenius Jens Christian

Abstract excerpt

BACKGROUND: The innate immune system encompasses various recognition molecules able to sense both exogenous and endogenous danger signals arising from pathogens or damaged host cells. One such pattern-recognition molecule is M-ficolin, which is capable of activating the complement system through the lectin pathway. The lectin pathway is multifaceted with activities spanning from complement activation to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23209787
DOI: 10.1371/journal.pone.0050585
PMCID: PMC3509001

Genes

FCN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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