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Article

Functional SNPs in the human ficolin (FCN) genes reveal distinct geographical patterns.

Molecular immunology - 1 May 2008

Hummelshøj Tina, Munthe-Fog Lea, Madsen Hans O, Garred Peter

Abstract excerpt

The ficolin protein family comprises three different molecules encoded by the FCN1, FCN2, and FCN3 genes, respectively, that play roles in innate immunity. The FCN genes in Caucasians are polymorphic and genetic variations may have functional consequences both in relation to function and concentration. The ethnic diversity of the FCN genes is unknown. The promoter and coding regions of the FCNs genes were...

Topics

Alleles
Ethnicity
Exons
Genetic Variation
Genotype
Haplotypes
Humans
Lectins
Linkage Disequilibrium
Polymorphism, Single Nucleotide
Promoter Regions, Genetic
Ficolins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18289682
DOI: 10.1016/j.molimm.2008.01.003

Genes

FCN1
FCN2
FCN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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