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Article

Extremes of L-ficolin concentration in children with recurrent infections are associated with single nucleotide polymorphisms in the FCN2 gene.

Clinical and experimental immunology - 1 Oct 2007

Cedzynski M, Nuytinck L, Atkinson A P M, St Swierzko A, Zeman K, Szemraj J, Szala A, Turner M L, Kilpatrick D C

Abstract excerpt

L-ficolin (also called ficolin-2, P35 or hucolin) is a soluble pattern recognition molecule of suspected importance in anti-microbial immunity. It activates the lectin pathway of complement and acts as an opsonin. l-ficolin, encoded by the FCN2 gene, recognizes microbial polysaccharides and glycoconjugates rich in GlcNAc or GalNAc. We report here data concerning four single nucleotide polymorphisms (SNPs) of the...

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Source

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Identifiers

PMID: 17680820
DOI: 10.1111/j.1365-2249.2007.03471.x
PMCID: PMC2219292

Genes

FCN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Extremes of L-ficolin concentration in children with recurrent infections are associated with single nucleotide polymorphisms in the FCN2 gene.PMID 17680820Read ↗

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