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Article

Elucidating the interactions between the adhesive and transcriptional functions of beta-catenin in normal and cancerous cells.

Journal of theoretical biology - 7 Jul 2007

van Leeuwen Ingeborg M M, Byrne Helen M, Jensen Oliver E, King John R

Abstract excerpt

Wnt signalling is involved in a wide range of physiological and pathological processes. The presence of an extracellular Wnt stimulus induces cytoplasmic stabilisation and nuclear translocation of beta-catenin, a protein that also plays an essential role in cadherin-mediated adhesion. Two main hypotheses have been proposed concerning the balance between beta-catenin's adhesive and transcriptional functions:...

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Share to beta Catenin
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to Colorectal Neoplasms

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Source

Identifiers

PMID: 17382967
DOI: 10.1016/j.jtbi.2007.01.019

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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