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Article

Wnt pathway mutations selected by optimal beta-catenin signaling for tumorigenesis.

FEBS letters - 26 Jun 2006

Cho Kwang-Hyun, Baek Songjoon, Sung Myong-Hee

Abstract excerpt

Mutations in components of the Wnt/beta-catenin pathway are observed to be the earliest initiating event for most colorectal tumors. The majority of the mutations occur in the tumor suppressor adenomatous polyposis coli (APC), even though there are other genes that are capable of modulating the p...

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Identifiers

PMID: 16764864
DOI: 10.1016/j.febslet.2006.05.053

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16764864-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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