Article
Monomeric α-catenin links cadherin to the actin cytoskeleton.
Nature cell biology - 1 Mar 2013
Desai Ridhdhi, Sarpal Ritu, Ishiyama Noboru, Pellikka Milena, Ikura Mitsuhiko, Tepass Ulrich
Abstract excerpt
The linkage of adherens junctions to the actin cytoskeleton is essential for cell adhesion. The contribution of the cadherin-catenin complex to the interaction between actin and the adherens junction remains an intensely investigated subject that centres on the function of α-catenin, which binds to cadherin through β-catenin and can bind F-actin directly or indirectly. Here, we delineate regions within Drosophila...
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