Article

Construction and Experimental Validation of a Petri net Model of Wnt/β-catenin Signaling

2016-03-21

Abstract excerpt

The Wnt/β-catenin signaling pathway is important for multiple developmental processes and tissue maintenance in adults. Consequently, deregulated signaling is involved in a range of human diseases including cancer and developmental defects. A better understanding of the intricate regulatory mechanism and effect of physiological (active) and pathophysiological (hyperactive) WNT signaling is important for predicting...

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Literature Corpus work: 9876641a-3e5c-5948-bf0c-e6679be9a700
DOI: 10.1101/044966

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