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Article

The oncogenic activation of beta-catenin.

Current opinion in genetics & development - 1 Feb 1999

Polakis P

Abstract excerpt

The activation of beta-catenin to an oncogenic state can result from the inactivation of the tumor suppressor adenomatous polyposis coli (APC), by direct mutation in the beta-catenin gene, or by the activation of wnt receptors. Once activated, beta-catenin most likely promotes tumor progression t...

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Share to beta Catenin
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Source

Identifiers

PMID: 10072352
DOI: 10.1016/s0959-437x(99)80003-3

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10072352-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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