Article
The CRHR1 gene: a marker for suicidality in depressed males exposed to low stress.
Genes, brain, and behavior - 1 Feb 2008
Wasserman D, Sokolowski M, Rozanov V, Wasserman J
Abstract excerpt
The risk of suicide, which causes about 1 million deaths each year, is considered to augment as the levels of stress increase. Dysregulation in the stress response of the hypothalamic-pituitary-adrenocortical (HPA) axis, involving the corticotrophin-releasing hormone (CRH) and its main receptor (CRHR1), is associated with depression, frequent among suicidal males. Here we have analyzed single nucleotide...
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