Article
Family-based study of AVPR1B association and interaction with stressful life events on depression and anxiety in suicide attempts.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jul 2013
Ben-Efraim Yair J, Wasserman Danuta, Wasserman Jerzy, Sokolowski Marcus
Abstract excerpt
The cortisol response to psychosocial stress may become dysregulated in stress-related disorders. It is potentiated by pituitary secretion of adrenocorticotropic hormone (ACTH), which is, in part, regulated by arginine vasopressin receptor-1B (AVPR1B). AVPR1B variants were previously reported to associate with mood and anxiety disorders. This study aims, for the first time, to investigate association of AVPR1B...
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